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What they found: In the control group 70 % of rats died within 30 days In the BPC-157 group only 10 % died Histology: faster formation of collaterals, normalization of portal vein pressure, 80 % reduction in liver thromboses Why it matters: These are extreme conditions

Knockdown studies in CNS endothelium indicated activation of the downstream effector eNOS as the principal mechanism underlying the effects of VEGF-A on the BBB

10.1111/j.1600-0609.2012.01779.x 171

[Google Scholar] 18.Gu X, Ying J, Min B, Cain JP, Davis P, Willey P, Navratilova E, Yamamura HI, Porreca F, Hruby VJ