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M., Dietrich, B., and Hiersemenzel, R

from the NIH and Wellcome trust

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[73] carried out a small placebo-controlled trial to evaluate the efficacy of whole-plant extracts of Cannabis sativa to compare delta-9-THC, CBD, and 1:1 delta-9-THC/CBD in 24 subjects consisting mainly of patients with MS ( n = 18), but also including subjects spinal cord injury ( n = 4), brachial plexus damage ( n = 1), and limb amputation due to neurofibrobromatosis ( n = 1)

Its antimelanogenic properties shift melanin production from darker eumelanin to lighter pheomelanin, but have only minimal effects