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The breakdown of tyrosinase blocks the synthesis of colour pigments

The slices were then transitioned into a serum-free medium consisting of Advanced DMEM/F-12 with 2% B-27 supplement [Thermo Fisher Scientific, #17504044] and 1% N-2 supplement [Thermo Fisher Scientific, #17502048] and cultured for up to 6 weeks

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Notably, substantial evidence indicates that cognitive impairment in patients with kidney dysfunction can be partially reversed with dialysis (63) and kidney transplantation (64)

then, investigations into possible causes can take time and may feel invasive and defeating