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Iron has also been suspected as a culprit in the increased oxidative stress and lesions of dopaminergic neurons because of its potent reductive property (Jenner et al., 1992)

In contrast, PPMS is defined by a gradual and continuous worsening of neurological function from disease onset, without distinct relapses or remissions

It has been hypothesized that the TGF pathway could play a role in COPD pathogenesis, but its role is not completely understood [40]

H., Culotta, K
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HepG2 were seeded at a density of 10.000 cells/cm 2
