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observed elevated chemokine levels in patients with GD ( 2+ levels ( In summary, abnormal levels of GD-related inflammatory factors can disrupt the BBB before mediating the formation of neuroinflammation through multiple pathways, such as activation of central microglia and recruitment of immune cells, which can cause nerve damage and increase susceptibility to depression

Cell Mol Immunol 18 , 7391 (2021)

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