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Similar content being viewed by others Main The activation of nucleic-acid-sensing endosomal Toll-like receptors (TLRs) and late endosomal-initiated signaling are central mechanisms in innate immunity, inflammation and autoimmunity 1,2,3,4,5,6,7

Goyal A, Sharma A, Kaur J, Kumari S, Garg M, Sindhu RK, et al

A hangover is caused by an accumulation of toxins in the body that build up as a result of alcohol consumption

Gallstone-related bowel obstruction (ileus) also requires urgent medical treatment with surgical stone removal and repair of the intestinal wall, and sometimes cholecystectomy either as part of the same procedure or later (Turner 2018)

Fumarate, or fumaric acid, is an important compound, which is also naturally present in the body

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