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The fact that GSH production is required during conditions that cause overproduction of ERgenerated ROS suggests a role for GSH in their elimination

Wong BX, Ayton S, Lam LQ et al (2014a) A comparison of ceruloplasmin to biological polyanions in promoting the oxidation of Fe (2+) under physiologically relevant conditions

The extracellular degradation of GSH occurs on the surface of the cells that express the enzyme -glutamyl transpeptidase and the dipeptidases found in the external plasma membrane (1) (Figure 5)

Advanced nano-formulations and antibodydrug conjugates have also substantially improved their bioavailability, making them promising candidates for future translational research

Some of the metabolic effects of LA are secondary to its regulatory effect on these pathways

doi: 10.1016/S0261-5614(97)80015-5