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Thus, while the additional studies will be done, we could suggest, based on the role of NO-system (Toda and Nakanishitoda, 2007
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e h ) Quantification of regional BBB permeability in the right temporal lobe (p = 0.037 Brain Fog (+) vs Recovered), left temporal lobe (p = 0.036 Brain Fog (+) vs Recovered), right frontal cortex (p = 0.039 Brain Fog (+) vs Brain Fog (-)) and left frontal cortex (p = 0.033 Brain Fog (+) vs Brain Fog (-)

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Taken together, this study found that at a 3 week timepoint, cuprizone pellets were more efficacious than cuprizone powder at producing astrocyte reactivity, microglial activation, oxidative stress, tissue swelling, and a reduction in the density of mature oligodendrocytes and demyelination when compared to control feeds, particularly in the caudal corpus callosum