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As we can see in the study Differences in cortisol awakening response on work days and weekends in women and men from the Whitehall II cohort , the subjects had higher cortisol levels on work days, as opposed to weekends, when levels were lower

Schlaeppi et al., 2008)

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This finding was mechanistically supported by an enhanced antifungal effect of fluconazole in a VVC vaginal epithelial cell model and mouse model when administered together with vitamin B complex injection 81