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Apart from neuroinflammation, 6-OHDA-treated rats also show decreased circulating T reg cells, indicating that this model can reflect aspects of human PD (174)

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The SNA is the well-known AuNP core/nucleotide shell nanoparticles that have be extensively studied as siRNA delivery system for the gene therapy of various cancers, including cutaneous tumors, glioblastoma, diabetes, and skin inflammation because of its low toxicity, low immunogenicity and persistent gene knockdown 27,56

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