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However, excessive mechanical stress and impingement can upregulate MMP expression, leading to increased collagen degradation and weakening of the ACL

This stack is widely studied because it combines two different regenerative pathways

Vitamin E, comprising tocopherols and tocotrienols, has free radical-scavenging and anti-inflammatory effects

PARP1 uses NAD+ during DNA repair to blend poly(ADP-ribose) chains that bring repair proteins to damaged DNA sites

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Total RNA samples were extracted by using the Maxwell Total RNA Purification kit, and RNA-Seq was performed at the GENEWIZ (HI-SEQ) next-generation sequencing platform