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[DOI] [PMC free article] [PubMed] [Google Scholar] 44.Leffler DA, Kelly CP, Green PHR, Fedorak RN, DiMarino A, Perrow W, Rasmussen H, Wang C, Bercik P, Bachir NM, Murray JA

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Cellular Aging & Longevity NAD+ is crucial for activating sirtuins, proteins that regulate aging and inflammation, and promote healthy cell function

Laboratory studies have highlighted possible roles in apoptosis regulation, insulin signaling, proteasome activity, and neurodegenerative disease models

2021 (Nature Communications) This study asked whether MOTS-c could restore physical performance in aged mice

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