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Quinone moiety Quinone moiety has also been utilized to develop hypoxia-triggered prodrug molecules owing to its ability to undergo electronic rearrangement to cleave covalent bonds under hypoxic conditions 123

Skin is the biggest organ of the human body, which provides maintenance of bodily fluid homeostasis and acts as a physical barrier against the entry of microorganisms [39]

Research should focus more on identifying specific microbial signatures or metabolites that can serve as early biomarkers for PD detection

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Do not shake vigorously, as agitation can denature the longer protein chains

Estriol has little estrogen agonist activity for the same reason [4, 15]
