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Description
Vitamins B, D, and folic acid Hyperhomocysteinemia is characterized by enhanced levels of non-proteinogenic -amino acid homocysteine, an intermediate in methionine metabolism
2018 Apr 1;172(4):336-344

[1] [3] If left untreated, some of these changes can become permanent

Current state of the art in peptide-based gene delivery
A more recent advance is mtDNA base editing, which utilizes engineered deaminase enzymes (e.g., DddA-derived cytosine base editors) to catalyze CG to TA base conversions in double-stranded mtDNA without creating double-strand breaks
