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Oxidative stress from free radicals formation may play a role in creating atherosclerotic plaques

Made up of three amino acids - glutamine, glycine and cysteine, it is naturally produced by the liver and has a number of functions

NAD+ metabolism and its roles in cellular processes during ageing

This study can guide future studies on the importance of monitoring the levels of pyroglutamic acidosis in critical patients with septic shock in order to preserve the oxidative status and its evolution during the stay in the ICU.

The authors highlight potential new therapeutic targets and discuss drug candidates that are in development for this debilitating diabetic complication.

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