glutathione toxicity treatment Participation in the Prevention of Cardiovascular Diseases Reducing the effects of drug
Description
Nature, 464(7286), 297301
Venditti P, Di Stefano L, Di Meo S
Rather than canonically activating downstream proinflammatory cytokines, STING promotes autophagic degradation of GPX4, thereby triggering neuronal ferroptosis (Woo et al., 2024)
2018;21(1s):177s-191s
Thus, the degree of lipidome unsaturation can serve as a proxy for ferroptosis sensitivity in different cell types and populations
The review also documents neuroprotective effects, including peripheral nerve regeneration after transection and counteraction of the otherwise progressing course following traumatic brain injury
