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It positively correlates with plasma levels of bile acids and hepatic mRNA expression of cholesterol 7 alpha-hydroxylase (CYP7A1) in mice, which trigger hepatic lipogenesis and hepatic steatosis via the bile acid-mediated hepatic farnesoid X receptor (FXR) signaling pathway [113]

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Tesamorelin is FDA-approved for adult visceral fat reduction in HIV-associated lipodystrophy

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Blue nevus There are four tan junctional NMN and one bluish-black round lesion on the cheek of a 17-year-old girl

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