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Baseline characterization of the WT, heterozygous (HE) and homozygous (HO) Chac1 KI mice showed no obvious abnormality in growth ( Fig 2A and 2B ), body composition ( Fig 2C and 2D ), and weight of heart, lung, liver, and skeletal muscles (gastrocnemius and tibialis anterior (TA)) ( Fig 2E and 2F ) in both females and males

Tolerance to heat stress has been ascribed to elevated antioxidant enzymes' activity in many crop plants (Rainwater et al., 1996

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4), which is the first data to show that CD36 specifically in muscle is directly necessary for palmitate uptake and oxidation during muscle contractions

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