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Emerging translational studies and early clinical evidence suggest that oral -ketoglutarate supplementation, following hepatic metabolism and systemic release, may confer protective effects against aging-associated disorders, including muscle decline (Gyanwali et al., 2022)

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Interestingly, we discovered that such decreases in GSH levels during ferroptosis do not occur immediately on erastin treatment, despite dramatic changes in cellular morphology (Fig

10.3389/fphys.2017.01040 91 NaziroluM.CiB.OzglC

[DOI] [PMC free article] [PubMed] [Google Scholar] 27.Gojkovic S, Krezic I, Vrdoljak B, Malekinusic D, Barisic I, Petrovic A, et al

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