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The anti-inflammatory effect protects follicles from damage while creating conditions favorable for regrowth

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Measurement of NVC in humans To evaluate NVC responses, a transcranial Doppler ultrasound system (DWL Multi-Dop T digital, Singen, Germany) with 2-MHz transducers was used
Chapman LE, Darling AL, Brown JE (2015) The association between the biguanide drug metformin and vitamin B 12 deficiency in diabetic patients: a systematic review

Oral vitamin B12 is generally safe to take at recommended doses