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The loss of negative charge could reduce solubility and lead to a higher mitochondrial accumulation of cyanine dyes and thus higher ROS production in the dark

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G9200, G9201, G9202 Caspase-Glo 3/7 Assay System An easy-to-use, plate-based luminescent assay for detecting caspase-3/7 activity

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doi: 10.1186/s40168-017-0271-9

Furthermore, expression of SLC7A11, a GSTO1 and C1-27 target gene, was increased in C1-27 -treated tumours indicating target engagement (Fig
