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Genetic predisposition : Those with a family history of melasma or other pigmentation disorders may be more susceptible because of inherited traits

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Peptides derived from the solvent-exposed loops 3 and 4 of BDNF bind TrkB and p75(NTR) receptors and stimulate neurite outgrowth and survival

In addition, the antioxidant and anti-inflammatory effects of natural extract polyphenols (like resveratrol, quercetin, rutin, curcumin, etc.) have been widely reported (125)

DOI:10.1016/j.jhep.2009.03.024 77

Moreover, in light of studies demonstrating that GSPE protects against oxidative stress (39) and enhances the working memory and cognitive performance in a rat model of Alzheimers disease (30), we primarily assessed the effects against epilepsy-associated oxidative stress and cognitive decline