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Leveraging the low-cost, transportable and biocompatible nature of US will additionally avoid restricting these imaging-guided trans-BBB delivery modalities to the operating room and broaden their therapeutic impact in various clinical and non-clinical settings

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Development of clinical criteria for functional assessment to predict primary nonfunction of high-risk livers using normothermic machine perfusion
Sci Rep 10(1):6064

The effect of these variations needs to be clarified in future studies to achieve personal or disease-specific optimization of nanoparticle design for future clinical translation of this technology

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