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Introduce gradually over several weeks

"Proof of a causative effect of B12 supplements on acne development will require randomized control trials with enough subjects to see a significant effect, if one exists," he told Live Science

In addition, LEFSe at the genus level highlighted significant enrichment of Clostridiales bacterium Firm-14, Butyrivibrio , and Prevotellaceae NK3831 group in the HFT group, while the HFC group exhibited significant enrichment of Desulfovbrio and Quinella (Figure 10F)

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