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In various research settings, it plays a role in the antioxidant defense system of cells to protect them from damage caused by oxidative stress and free radicals

2018;38(5):BSR20180858

This was unlikely to be because particles from yeast were already associated with GSH as the cryo-EM structure of purified yeast-derived PV3-SC8 particles showed that there was no specific chemical entity bound at the GSH-binding site (Fig

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In the GPX catalytic site and during the initial step, the selenocysteine or cysteine gets oxidized to selenic or cysteinic acids