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Acknowledgements This study was supported by the National Natural Science Foundation of China (71671182), the National Key R&D Program of China (2018YFF0214704) and the Program for One-hundred Talent Program of the Chinese Academy of Sciences (Y5AA100A01)

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When supplements are used as part of a comprehensive treatment plan (with phototherapy or topical treatments), initial visible repigmentation often begins around 3 to 6 months