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Sleep disturbances are associated with daytime functional deficits and increased fatigue levels, as well as an increased risk of numerous age-related diseases, including cardiovascular disease, stroke, diabetes, major depression, and dementia [4]

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It is found that nicotine can induce human gingival fibroblasts (HGFs) to produce excessive ROS, and a higher level of phosphorylated JNK can be detected in a short time

Once reconstituted in solution, peptides degrade faster due to hydrolysis and should be refrigerated and used within a few weeks

The MicrobiotaGutBrain Axis. Physiological Reviews 99: 18772013

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