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In North America, the response rate to immune checkpoint inhibitors is 1520%, whereas in Asia, the response rate is slightly lower, at 1015% (26,27)

doi: 10.3390/ijms232213675 93

This offset increases as protein size decreases due to surface effects, which is consistent with our experimental measurements with CSOP (Fig

To view a copy of this license, visit About this article Cite this article Nakanishi, H., Hayakawa, Y., Kubota, Y

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Nitric oxide activates the cGMP pathway
