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In these models, it selectively stimulates GH release without raising ACTH or cortisol, increases bone mineral content, and shows partial rescue of glucocorticoid-induced nitrogen wasting

doi: 10.1523/JNEUROSCI.3885-07.2007

[DOI] [PMC free article] [PubMed] [Google Scholar] 165.Pfeffer P.E., Ho T.R., Mann E.H., Kelly F.J., Sehlstedt M., Pourazar J., Dove R.E., Sandstrom T., Mudway I.S., Hawrylowicz C.M

doi: 10.1007/s00044-023-03116-9

Freed Nrf2 translocates to the nucleus, where it binds Antioxidant Response Elements (AREs) in gene promoters, often dimerizing with small Maf proteins to form a transactivation complex