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Notably, pharmacological inhibition of Piezo1 with GsMTx4 or inhibition of downstream Rac1 activation significantly inhibited these signaling events, lowered proteinuria, and preserved cytoskeletal architecture in hypertensive and diabetic mouse models [94,100]

Free Radic Biol Med 14(3):313323

Rubio-Tapia A, Hill ID, Kelly CP, et al

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Investigators in regenerative science, tissue engineering, biomaterials science, and cellular aging biology may find GHK-Cu to be a compelling subject of further inquiryone that bridges endogenous biology and engineered research in innovative ways