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Initially, the carboxylate group on -glutamylcysteine is converted into an acyl phosphate by the transfer of an inorganic phosphate group of ATP to generate an acyl phosphate intermediate

[DOI] [PubMed] [Google Scholar] Piskounova E, Agathocleous M, Murphy MM, Hu Z, Huddlestun SE, Zhao Z, Leitch AM, Johnson TM, DeBerardinis RJ, Morrison SJ

The duration of the cycle with this peptide lasts 15 days, after which a break of 15 days is necessary and the intake can be resumed

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