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Subcutaneous or intramuscular shots bypass your digestive system completely

10.1038/s41598-018-26956-7 87 LiuM.LiL.ChuJ.ZhuB.ZhangQ.YinX.et al (2015)
The duration of semaglutide use varies, but many protocols continue for 40 to 68 weeks total
Jiang, L.-H., Shi, Y., Wang, L.-S

women typically need lower doses
doi: 10.1210/en.2008-1772