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3 Acetylation and deacetylation in kidney disease Acetylation, as one of the most extensively studied topics in PTM, primarily occurs on lysine residues and is categorized into two main types: histone acetylation and non-histone acetylation

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Nanomaterials 13:2486 Wang Y, Peng X, Hu J et al (2021) Low-dose colchicine in type 2 diabetes with microalbuminuria: a double-blind randomized clinical trial

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The most extensively studied of these is the 677CT polymorphism in the methylenetetrahydrofolate reductase ( MTHFR ) gene, first identified in 1995 as a risk factor for vascular disease and later linked to NTDs

Petrovic et al., 2011