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Additionally, this paper also summarized a variety of measures to intervene in related diseases by targeting the reduction of TMAO levels, including probiotics, prebiotics, antibiotics, anti-inflammatory drugs, antiplatelet agents, hypoglycemic agents, lipid-lowering drugs, Chinese herbal monomers, herbal extracts, and formulas

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55 The use of NBS for early detection of MCAD deficiency has revealed a more varied mutational and biochemical spectrum of MCAD deficiency than the studies done on clinically ascertained populations