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These results suggest that an HFD causes severe abnormal mitochondrial morphology and dysfunction, while antioxidants and dietary restriction protect mitochondria and reduce oxidative stress in obesity-related nephropathy

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Compared with WKY, SHR displayed downregulated caveolin-1 expression and increased NADPH-induced superoxide production, whereas eNOS activity was reduced

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They can help break down circulating immune complexes, degrade excess fibrin (which is highly relevant for the microclots seen in Long COVID), and modulate systemic cytokine levels