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231 Additionally, approximately one-third of the pathological mutations observed in the gene encoding tau (MAPT) have been reported to affect tau splicing and the ratio of tau isoforms containing three or four microtubule-binding domains (3R-tau to 4R-tau ratio)a ratio whose imbalance is linked to impaired microtubule dynamics in tauopathies such as AD

2016 Oct 28

The ultimate goal is to provide robust evidence for the long-term safety and efficacy of melatonin in preventing and treating vascular dysfunction

He describes it as a gastric pentadecapeptide synthesised from gastric juice, says its tolerated well even orally, and says injecting it at the site of an injury helps call platelets to that location (source)

Eisinger J, Clairet D

Neutrophil micrornas
