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This is important, as it means these people may need less medication to achieve the same blood levels of active ingredient as healthy people ( 23 )

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10.1073/pnas.95.6.3071 [DOI] [PMC free article] [PubMed] [Google Scholar] Qin H., Carroll V

In addition to its traditional function in erythropoiesis, recent findings suggest that EPO signaling also affects red blood cell metabolism and membrane composition via regulating oxidative stress responses, cytoskeletal architecture, and lipid remodeling (54)

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Conversely, glutathione treatment reduces in a dosedependent manner oxidative stress as indicated by the reduction in H 2 O 2 levels (23.66.1 mol/L versus 39.87.3 mol/L for 5 mM of glutathione