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Interface 2015, 12 (113), 20150891

Thus, although the combination of anti-complement therapies with other anti-cancer agents should be further investigated, the increasing number of studies that demonstrate the improved antitumor responses obtained combining complement inhibitionand in particular C5aR1 inhibitionwith chemotherapy and/or immunotherapy, together with our present results on paclitaxel-mediated C5aR1 activation, further sustain that a combined treatment with paclitaxel and C5aR1 inhibitors could be a promising therapeutic approach, not only to prevent CIPN and HSRs, but also to potentially obtain a synergistic effect on tumor progression

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doi: 10.1016/j.ejmech.2018.12.016 [DOI] [PubMed] [Google Scholar] [279].Chilelli NC, Ragazzi E, Valentini R, et al

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The product pictured is Biolongevity Labs BPC-157, a research-grade compound that matches the sourcing criteria discussed in this section, per-batch HPLC and mass spectrometry documentation, US manufacturing, and transparent certificate of analysis publication