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MDM2 ubiquitinates p53, resulting in the rapid degradation of p53 through the Ubproteasome pathway

Growth hormone secretagogues and endocrine regulation

R.KaltwasserB.TeliM

The desensitization may involve decreased expression of the proteins STIM2, Orai1, and Orai3 which support SOCE mechanism

Importantly, the relative activities of these regulons were consistently deregulated across most PFG and PEN clusters (Fig