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Animal and lab findings can explain biological pathways, but they do not confirm human safety or effectiveness

The Bioavailability Problem: Why Formulation Matters This is where many wellness enthusiasts run into a wall

10.1186/s12943-023-01825-8 [DOI] [PMC free article] [PubMed] [Google Scholar] Peschke J

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This mechanical effect complements the central nervous system effects, providing multiple reinforcing signals that reduce total food intake without requiring conscious effort