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In addition, phosphodiesterase-5 inhibitors (PDE-5i), popular among AAS users, were excluded, although they were thought to increase libido after AAS cessation

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75,76 GWAS have identified single nucleotide polymorphisms near genes GFRA2, HMGB1P46, and ZSCAN20-TLR12P in patients with PDPN (Fig

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