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Effects of biliary cannulation and buthionine sulfoximine pretreatment on the nephrotoxicity of p-aminophenol in the Fischer 334 rat

Briefly, MG detoxification is initiated by the non-enzymatic reaction of this toxic metabolite with a low-molecular-weight thiol such as reduced glutathione (GSH) or bacillithiol, forming a hemithioacetal

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These studies illustrate Cagrilintides potential for multi-receptor weight-loss mechanisms and form the basis for translational research
