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[16] [17] Whereas the latter directly act on the dopamine transporter (DAT) to inhibit the reuptake and/or induce the release of dopamine, bromantane instead acts via indirect genomic mechanisms to produce a rapid, pronounced, and long-lasting upregulation in a variety of brain regions of the expression of tyrosine hydroxylase (TH) and aromatic L-amino acid decarboxylase (AAAD) (also known as DOPA decarboxylase), key enzymes in the dopamine biosynthesis pathway
Elevated homocysteine levels can also increase the risk of stroke
[DOI] [PubMed] [Google Scholar] 42.Breslow MJ, Min-Lee K, Brown DR, Chacko VP, Palmer D, Berkowitz DE
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Severe cases of b12 overdose level may cause high blood pressure or heart palpitations
