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The sam1/sam1 mutant cells likely exhibited decreased growth in this condition due to downregulated CDC21 expression (fold change of 0.62, p-value=0.0247), which encodes thymidylate synthase, and/or because RNR complex inhibition could create dNTP pool imbalances which in concert with less Cdc21 could cause more difficulty to interconvert between some deoxyribonucleotides in these mutant cells, thereby creating sensitivity to this condition (Fig 13)

Please Note: Treatment is subject to consultation

This peptide engineering technique uses D-amino acids arranged in reverse order, making the peptide more resistant to enzymatic breakdown while preserving its biological activity

Food Chem 267:111118

Repurposing of a drug scaffold: identification of novel sila analogues of rimonabant as potent antitubercular agents

Warnings Do not exceed recommended dose