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Key MechanismsRedox Balance, Detoxification, & Neuroprotection Glutathione (GSH) governs cellular redox homeostasis and detoxifies reactive oxygen and nitrogen species (RONS), protecting neurons that are particularly vulnerable due to high metabolic demand and oxygen use

ROS are then transformed into less reactive products by antioxidative enzymes, while phase II conjugating enzymes, such as glutathione S-transferases (GSTs), participate in detoxification of their reactive secondary products [17]

10.3892/mmr.2021.12337 39 MagistrelliL.StorelliE.RasiniE.ContaldiE.ComiC.CosentinoM.et al (2020)

Some peptides regulate the hypothalamic-pituitary-gonadal axis more directly, optimizing gonadotropin release patterns and normalizing downstream hormone production

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98 This relationship has been hypothesized to result from vitamin Dassociated calcium channel proteins in the epithelium that play a role in calcium metabolism of the vestibular organ of the inner ear