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To rule out that the less protein-membrane interaction observed in hyh mice resulted from any physical or biochemical PM alteration associated with hyh phenotype, we performed a crossover protein-lipid interaction experiment

Localization of CYP2E1 to mitochondria enhances the local production of HER and ROS, particularly in hepatocytes, contributing to impaired mitochondrial integrity and function [34,35]

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Immunohistochemical staining (IHC) was performed on each tissue sample, which was fixed in 4% formalin immediately after removal and embedded in paraffin for IHC analysis using the standard staining procedure [29]

Redness or mild soreness at the injection site resolves within a few hours

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