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Patients with higher levels of gamma-glutamyl transferase, and particularly men, demonstrate a significantly higher risk for systemic sclerosis, according to data published in Nature Scientific Reports

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We propose patients who pause treatment may have testing repeated after 2 weeks, while those with resolving aminotransferase elevations may reinitiate omaveloxolone with stepwise dose titrations and testing every 2 weeks for 3 months

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