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The plant glutathione peroxidase enzymes (GPXs) may be involved in the detoxification of H 2 O 2 and organic hydroperoxides and in the regulation of the cellular redox homeostasis by maintaining the thiol/disulfide balance

[DOI] [PubMed] [Google Scholar] 120.Almeida V.D., Monteiro M.G., Oliveira M.G.M., Pomarico A.C., Bueno O.F.A., da Silva-Fernandes M.E

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An increase in temperature within PDAC tumor tissue drives alterations in lipid metabolism, including a decrease in PUFAs such as phosphatidylcholine plasmalogen (PC-P), attenuating lipid peroxidation and ferroptosis, and further drives gemcitabine resistance in PDAC through the p38-MAPK pathway [154]