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Grabarevic Z, Tisljar M, Artukovic B, Bratulic M, Dzaja P, Seiwerth S, et al

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Monocyte-derived and tissue-resident macrophages are decreased in quantity in GF mice or in mice that that are microbiota-depleted with antibiotics, implying a role for the microbiota in intestinal macrophage recruitment and differentiation 107

One study focused on Rho inhibitor p190RhoGAP, which is naturally synthesized in cells, to see how decreases in Rho signaling altered VEGFR-2 expression and if VEGFR-2 can be mechanically-activated (146)