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Preclinical studies demonstrate that dual targeting can amplify DAMP release, promote antigen presentation, and stimulate robust adaptive immune responses, potentially overcoming immune escape and therapeutic resistance (218)
Dehydroepiandrosterone (DHEA) or testosterone were used as substrates for 3-HSD or 17-HSD, respectively

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Even though only limited information is available regarding the regulation of GSTP1 by miRNAs, we believe that further investigations could contribute to the development of new therapeutic miRNA-based anticancer strategies
